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Below are some of the published research articles for the many symptoms, syndromes and or diseases where clinicians have reported their success with the MRT-LEAP protocol. 

Old Books

Irritable Bowl Syndrome (IBS)

1. Subtypes and Severity of Irritable Bowel Syndrome Are Not Related to Patients' Self-Reported Dietary Triggers: Results From an Online Survey in Dutch Adults

Iris RijnaartsBen J M WittemanErwin G ZoetendalCoen GoversNicole J W de WitNicole M de Roos

2. Diet and nutritional factors in inflammatory bowel diseases. Danuta Owczarek 1Tomasz Rodacki 1Renata Domagała-Rodacka 1Dorota Cibor 1Tomasz Mach 1.Affiliations expand

3. Diet and Nutrition in Pediatric Inflammatory Bowel Diseases.Ugo Cucinotta 1Claudio Romano 1Valeria Dipasquale 1. Affiliations expand

4. Is Personalized Dietary Therapy Effective for Individuals With Irritable Bowel Syndrome?Gustavo G Zarini 1Michael A McLean 1Savina I Delgado 1

Affiliations expand.

5. Use of the LEAP mediator release test to identify non-IgE mediated immunologic food reactions that trigger diarrhea predominant IBS symptoms results in marked improvement of symptoms through use of an elimination diet. American Journal of Gastroenterology: October 2004 – Volume 99 – Issue – P S277-S278.

Chrohn's Disease

1. Clinical and Anthropometric Improvements with a Tailored Dietary Approach in Pediatric Crohn's Disease. Gustavo G Zarini, Jennifer Masters, Michael A McLean, Cory T Strobel.


1. Tailored Dietary Approach for Individuals With Migraine. Susan LinkeGustavo ZariniMichael McLeanJoan HoganPatrick Hogan, and Jan Patenaude. 

Curr Dev Nutr. 2021 Jun; 5(Suppl 2): 849.Published online 2021 Jun 7. doi: 10.1093/cdn/nzab047_012

2. November 2012 Issue Migraine Headaches — Here’s How to Identify Food Triggers and Reduce Debilitating Symptoms. By Karen Appold.Today’s Dietitian
Vol. 14 No. 11 P. 14

3. Migraine and Diet. Parisa Gazerani 1. Affiliations expand

4. Advances in genetics of migraine. Heidi G. SutherlandCassie L. Albury, and Lyn R. Griffiths. J Headache Pain. 2019; 20(1): 72.Published online 2019 Jun 21. doi: 10.1186/s10194-019-1017-9


1. Evaluating the Feasibility and Acceptability of the Lifestyle Enhancement for ADHD Program. Cindy Ola 1 2, Erin Gonzalez 1 2, Nguyen Tran 2, Tyler Sasser 1 2, Michelle Kuhn 2, Patrick A LaCount 2, Mark A Stein 1 2, Jason A Mendoza 2 3 4, Pooja S Tandon 2 3. Affiliations expand.

Celiac Disease

1. Six Reasons to Test for Celiac Disease Before Starting a Gluten-Free Diet. Dr. Amy Burkhart, M.D., R.D. 

2. American College of Gastroenterology Guidelines Update: Diagnosis and Management of Celiac Disease. Alberto Rubio-Tapia 1, Ivor D Hill 2, Carol Semrad 3, Ciarán P Kelly 4, Katarina B Greer 5, Berkeley N Limketkai 6, Benjamin Lebwohl 7 Affiliations expand.

3. Celiac & Gluten Sensitivity by Doctor's Data Vs LEAP MRT.

4. Eating, Diet, & Nutrition for Celiac Disease. 

5. Clinical and Anthropometric Improvements with a Tailored Dietary Approach in Pediatric Crohn's Disease. Gustavo G Zarini, Jennifer Masters, Michael A McLean, Cory T Strobel


1. Effectiveness of a Tailored Dietary Program in Subjects With Fibromyalgia. Jan Patenaude, Gustavo Zarini, Michael McLean, and Susan Linke. 

Curr Dev Nutr. 2021 Jun; 5(Suppl 2): 856.Published online 2021 Jun 7. doi: 10.1093/cdn/nzab047_019

2. Nutritional Interventions in the Management of Fibromyalgia Syndrome. Giuditta Pagliai,1,2,* Ilaria Giangrandi,1,2 Monica Dinu,1,2 Francesco Sofi,1,2 and Barbara Colombini1. Nutrients. 2020 Sep; 12(9): 2525. Published online 2020 Aug 20. doi: 10.3390/nu12092525


1. A modified Mediterranean dietary intervention for adults with major depression: Dietary protocol and feasibility data from the SMILES trial. Rachelle S. Opie,Adrienne O'NeilFelice N. Jacka Josephine Pizzinga &Catherine Itsiopoulos. Pages 487-501 | Published online: 19 Apr 2017

2. Personalized Dietary Intervention for Women with Depression and Anxiety M. McLean,G. Zarini,S. Linke. 


1. Silent Reflux Disease By Lauren O’Connor, MS, RDN, RYT. Today’s Dietitian Vol. 24 No. 8 P. 40 


1. Clinical Improvement of IBS, Migraine, Fibromyalgia and Arthritis Using Elimination Diets Based on Mediator Release Blood Testing. J. Patenaude, D. Bright. 


1. The Lifestyle Eating and Performance (LEAP) Program for Improving Quality of Life in Women With PCOS: A Pilot Study of Dietitian-Directed Therapy

Author links open overlay panelNadine Braunstein 1, Michal Hogan 2, Rafael Diaz Escamilla 3.

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